HEART Pathway Accelerated Diagnostic Protocol Implementation: Prospective Pre-Post Interrupted Time Series Design and Methods

Simon A Mahler   ^{1 *} , MD, MS ;   Gregory L Burke   ^{2 *} , MD ;   Pamela W Duncan   ^{3 *} , PhD ;   Larry D. Case   ^{2 *} , PhD ;   David M Herrington   ^{4 *} , MD, MHS ;   Robert F Riley   ^{4 *} , MD, MS ;   Brian J Wells   ⁵ , MD, PhD ;   Brian C Hiestand   ^{1 *} , MD, MPH ;   Chadwick D Miller   ^{1 *} , MD, MS

¹ Wake Forest School of Medicine, Department of Emergency Medicine, Winston Salem, NC, United States

² Wake Forest School of Medicine, Public Health Sciences, Winston Salem, NC, United States

³ Wake Forest School of Medicine, Department of Neurology, Sticht Center on Aging, Gerontology, and Geriatric Medicine, Winston Salem, NC, United States

⁴ Wake Forest School of Medicine, Department of Internal Medicine, Division of Cardiovascular Medicine, Winston Salem, NC, United States

⁵ Wake Forest School of Medicine, Translational Science Institute, Family and Community Medicine, Epidemiology and Prevention, Winston Salem, NC, United States

*these authors contributed equally