Varenicline and Bupropion for Long-Term Smoking Cessation (the MATCH Study): Protocol for a Real-World, Pragmatic, Randomized Controlled Trial

Laurie Zawertailo   ^{1, 2} , PhD ;   Tara Mansoursadeghi-Gilan   ¹ , MSc ;   Helena Zhang   ^{1, 2} , MSc ;   Sarwar Hussain   ² , MSc ;   Bernard Le Foll   ^{1, 3, 4, 5, 6, 7, 8} , MD, PhD ;   Peter Selby   ^{2, 4, 9} , MBBS

¹ Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada

² Nicotine Dependence Service, Centre for Addiction and Mental Health, Toronto, ON, Canada

³ Translational Addiction Research Laboratory, Centre for Addiction and Mental Health, Toronto, ON, Canada

⁴ Lunenfeld Tanenbaum Research Institute, Sinai Health Systems, Toronto, ON, Canada

⁵ Department of Psychiatry, University of Toronto, Toronto, ON, Canada

⁶ Department of Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada

⁷ Acute Care Program, Centre for Addiction and Mental Health, Toronto, ON, Canada

⁸ Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada

⁹ Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada