VEROnA Protocol: A Pilot, Open-Label, Single-Arm, Phase 0, Window-of-Opportunity Study of Vandetanib-Eluting Radiopaque Embolic Beads (BTG-002814) in Patients With Resectable Liver Malignancies

Laura Beaton   ¹ , MBBS, MRCP, FRCR ;   Henry F J Tregidgo   ² , PhD ;   Sami A Znati   ¹ , BSc ;   Sharon Forsyth   ³ , BSc ;   Matthew J Clarkson   ² , PhD ;   Steven Bandula   ⁴ , PhD ;   Manil Chouhan   ⁴ , MBBS, BSc (Hons), MRCS, FRCR, PhD ;   Helen L Lowe   ⁵ , PhD ;   May Zaw Thin   ⁶ , MBBS ;   Julian Hague   ⁷ , FRCR ;   Dinesh Sharma   ⁸ , MBBS, FRCS Ed, FRCS (Gen Surg) ;   Joerg-Matthias Pollok   ^{9, 10} , MD, FRCS (Glasg), PhD ;   Brian R Davidson   ^{9, 10} , MBChB, MD ;   Jowad Raja   ⁷ , MBChB, MRCS, FRCR ;   Graham Munneke   ⁷ , MBBS, MRCS, FRCR ;   Daniel J Stuckey   ⁶ , BSc, PhD ;   Zainab A Bascal   ¹¹ , BSc, PhD ;   Paul E Wilde   ¹¹ , BSc (Hons), MSc ;   Sarah Cooper   ¹¹ , MSc ;   Samantha Ryan   ¹¹ , BSc (Hons), MSc, Cstat ;   Peter Czuczman   ¹¹ , BSc ;   Eveline Boucher   ¹¹ , MD, PhD ;   John A Hartley   ¹ , PhD ;   Andrew L Lewis   ¹¹ , BSc, PhD ;   Marnix Jansen   ¹ , MD, MSc, PhD ;   Tim Meyer   ^{1, 12} , BSc, MBBS, MRCP, PhD ;   Ricky A Sharma   ¹³ , MB BChir, MRCP, FRCR, FRCP, PhD

¹ University College London Cancer Institute, University College London, London, United Kingdom

² Department of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom

³ Cancer Research UK University College London Cancer Trials Centre, London, United Kingdom

⁴ University College London Centre for Medical Imaging, University College London, London, United Kingdom

⁵ University College London Experimental Cancer Medicine Centre Good Clinical Laboratory Practice Facility, University College London, London, United Kingdom

⁶ Centre for Advanced Biomedical Imaging, University College London, London, United Kingdom

⁷ University College London Hospitals NHS Foundation Trust, London, United Kingdom

⁸ Division of Transplantation and Immunology, Royal Free Hospital NHS Foundation Trust, London, United Kingdom

⁹ Division of Surgery and Interventional Science, University College London, London, United Kingdom

¹⁰ Hepatopancreatobiliary Surgery and Liver Transplantation, Royal Free Hospital NHS Foundation Trust, London, United Kingdom

¹¹ Biocompatibles UK Ltd, London, United Kingdom

¹² Department of Oncology, Royal Free Hospital NHS Foundation Trust, London, United Kingdom

¹³ National Institute for Health Research University College London Hospitals Biomedical Centre, University College London Cancer Institute, London, United Kingdom