Efficacy and Safety of Medicines Targeting Neurotrophic Factors in the Management of Low Back Pain: Protocol for a Systematic Review and Meta-analysis

Rodrigo R N Rizzo   ^{1, 2} , MSc ;   Michael C Ferraro   ^{1, 2} , BSc(Hons) ;   Michael A Wewege   ^{1, 2} , MSc ;   Aidan G Cashin   ^{2, 3} , BExPhys ;   Hayley B Leake   ^{2, 4} , BPhysio(Hons) ;   Edel T O’Hagan   ^{2, 3} , MSc ;   Matthew D Jones   ^{1, 2} , PhD ;   Sylvia M Gustin   ^{2, 5} , PhD ;   James H McAuley   ^{1, 2} , PhD

¹ School of Medical Sciences, University of New South Wales, Sydney, Australia

² Centre for Pain IMPACT, Neuroscience Research Australia, Sydney, Australia

³ Prince of Wales Clinical School, University of New South Wales, Sydney, Australia

⁴ IIMPACT in Health, University of South Australia, Adelaide, Australia

⁵ School of Psychology, University of New South Wales, Sydney, Australia