Published on in Vol 11 , No 10 (2022) :October

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/37452, first published .
The Fetal Growth Restriction at Term Managed by Angiogenic Factors Versus Feto-Maternal Doppler (GRAFD) Trial to Avoid Adverse Perinatal Outcomes: Protocol for a Multicenter, Open-Label, Randomized Controlled Trial

The Fetal Growth Restriction at Term Managed by Angiogenic Factors Versus Feto-Maternal Doppler (GRAFD) Trial to Avoid Adverse Perinatal Outcomes: Protocol for a Multicenter, Open-Label, Randomized Controlled Trial

The Fetal Growth Restriction at Term Managed by Angiogenic Factors Versus Feto-Maternal Doppler (GRAFD) Trial to Avoid Adverse Perinatal Outcomes: Protocol for a Multicenter, Open-Label, Randomized Controlled Trial

Pablo Garcia-Manau 1 * , MD ;   Manel Mendoza 1 * , MD, PhD ;   Erika Bonacina 1 , MD ;   Raquel Martin-Alonso 2, 3 , MD ;   Lourdes Martin 4 , MD ;   Ana Palacios 5, 6 , MD, PhD ;   Maria Luisa Sanchez 7 , MD ;   Cristina Lesmes 8 , MD, PhD ;   Ivan Hurtado 9 , MD ;   Esther Perez 10 , MD ;   Albert Tubau 11 , MD ;   Patricia Ibañez 12 , MD ;   Marina Alcoz 13 , MD ;   Nuria Valiño 14 , MD, PhD ;   Elena Moreno 15 , MD ;   Carlota Borrero 16 , MD, PhD ;   Esperanza Garcia 17 , MD ;   Eva Lopez-Quesada 18 , MD, PhD ;   Sonia Diaz 19 , MD ;   Jose Roman Broullon 20 , MD, PhD ;   Mireia Teixidor 21 , MD ;   Carolina Chulilla 22 , MD ;   Maria M Gil 2, 3 , MD, PhD ;   Monica Lopez 4 , MD ;   Amparo Candela-Hidalgo 5, 6 , MD ;   Andrea Salinas-Amoros 7 , MD ;   Anna Moreno 8 , MD ;   Francesca Morra 9 , MD ;   Oscar Vaquerizo 10 , MD ;   Beatriz Soriano 11 , MD ;   Marta Fabre 12 , MD ;   Elena Gomez-Valencia 13 , MD ;   Ana Cuiña 14 , MD ;   Nicolas Alayon 15 , MD ;   Jose Antonio Sainz 16 , MD, PhD ;   Angels Vives 17 , MD ;   Esther Esteve 18 , MD ;   Vanesa Ocaña 19 , MD ;   Miguel Ángel López 20 , MD, PhD ;   Anna Maroto 21 , MD, PhD ;   Elena Carreras 1 , MD, PhD

1 Maternal Fetal Medicine Unit, Department of Obstetrics , Vall d’Hebron Barcelona Hospital Campus , Universitat Autònoma de Barcelona , Barcelona , ES

2 Maternal Fetal Medicine Unit, Department of Obstetrics , Hospital Universitario de Torrejón , Madrid , ES

3 School of Medicine , Universidad Francisco de Vitoria , Madrid , ES

4 Maternal Fetal Medicine Unit, Department of Obstetrics , Hospital Universitari de Tarragona Joan XXIII , Universitat Rovira i Virgili , Tarragona , ES

5 Department of Obstetrics , Alicante University General Hospital , Miguel Hernandez University , Alicante , ES

6 Alicante Institute for Health and Biomedical Research , Alicante , ES

7 Maternal Fetal Medicine Unit, Department of Obstetrics , Hospital Clínico Universitario Virgen de la Arrixaca , Universidad de Murcia , Murcia , ES

8 Maternal Fetal Medicine Unit, Department of Obstetrics , Parc Taulí Hospital Universitari , Universitat Autònoma de Barcelona , Sabadell , ES

9 Maternal Fetal Medicine Unit, Department of Obstetrics , Hospital Universitari Germans Trias i Pujol , Universitat Autònoma de Barcelona , Badalona , ES

10 Maternal Fetal Medicine Unit, Department of Obstetrics , Hospital Universitario de Cabueñes , Universidad de Oviedo , Gijón , ES

11 Maternal Fetal Medicine Unit, Department of Obstetrics , Hospital Universitari Son Llàtzer , Universitat de les Illes Balears , Palma de Mallorca , ES

12 Aragon Institute for Health Research , Department of Obstetrics , Hospital Clínico Universitario Lozano Blesa , Zaragoza , ES

13 Maternal Fetal Medicine Unit, Department of Obstetrics , Fundació Althaia , Universitat de Vic , Manresa , ES

14 Maternal Fetal Medicine Unit, Department of Obstetrics , Hospital Universitario de A Coruña , Universidade da Coruña , A Coruña , ES

15 Maternal Fetal Medicine Unit, Department of Obstetrics , Hospital General Universitario de Elche , Universidad Miguel Hernández , Elche , ES

16 Maternal Fetal Medicine Unit, Department of Obstetrics , Hospital Universitario Virgen de Valme , Universidad de Sevilla , Sevilla , ES

17 Maternal Fetal Medicine Unit, Department of Obstetrics , Consorci Sanitari de Terrassa , Universitat Internacional de Catalunya , Terrassa , ES

18 Maternal Fetal Medicine Unit, Department of Obstetrics , Hospital Universitari Mútua Terrassa , Universitat de Barcelona , Terrassa , ES

19 Maternal Fetal Medicine Unit, Department of Obstetrics , Hospital Universitario de Getafe , Universidad Europea de Madrid , Getafe , ES

20 Maternal Fetal Medicine Unit, Department of Obstetrics , Hospital Universitario Puerta del Mar , Universidad de Cádiz , Cádiz , ES

21 Maternal Fetal Medicine Unit, Department of Obstetrics , Hospital Universitari de Girona Doctor Josep Trueta , Universitat de Girona , Girona , ES

22 Maternal Fetal Medicine Unit, Department of Obstetrics , Hospital Universitario Nuestra Señora de Candelaria , Universidad de La Laguna , Santa Cruz de Tenerife , ES

*these authors contributed equally

Corresponding Author:

  • Manel Mendoza, MD, PhD
  • Maternal Fetal Medicine Unit, Department of Obstetrics
  • Vall d’Hebron Barcelona Hospital Campus
  • Universitat Autònoma de Barcelona
  • Passeig de la Vall d’Hebron, 119-129
  • Barcelona
  • ES
  • Phone: 34 934893085
  • Email: manel.mendoza@vallhebron.cat