Diagnostic Ability of a Smartphone App for Dry Eye Disease: Protocol for a Multicenter, Open-Label, Prospective, and Cross-sectional Study

Ken Nagino   ^{1, 2, 3} , MS ;   Yuichi Okumura   ^{2, 3} , MD, PhD ;   Masahiro Yamaguchi   ² , MD, PhD ;   Jaemyoung Sung   ^{2, 4} , MS ;   Masashi Nagao   ^{5, 6, 7} , MD, PhD ;   Kenta Fujio   ^{2, 3} , MD ;   Yasutsugu Akasaki   ^{2, 3} , MD ;   Tianxiang Huang   ^{2, 3} , MD ;   Kunihiko Hirosawa   ^{2, 3} , MD ;   Masao Iwagami   ⁸ , MD, MPH, MSc, PhD ;   Akie Midorikawa-Inomata   ¹ , RN, MPH, PhD ;   Keiichi Fujimoto   ^{2, 3} , MD, PhD ;   Atsuko Eguchi   ¹ , PhD ;   Yukinobu Okajima   ⁹ , MD, PhD ;   Koji Kakisu   ⁹ , MD, PhD ;   Yuto Tei   ⁹ , MD, PhD ;   Takefumi Yamaguchi   ¹⁰ , MD, PhD ;   Daisuke Tomida   ¹⁰ , MD, PhD ;   Masaki Fukui   ¹⁰ , MD, PhD ;   Yukari Yagi-Yaguchi   ¹⁰ , MD, PhD ;   Yuichi Hori   ⁹ , MD, PhD ;   Jun Shimazaki   ¹⁰ , MD, PhD ;   Shuko Nojiri   ⁶ , MSc, PhD ;   Yuki Morooka   ^{2, 3} , MD ;   Alan Yee   ^{2, 3} , MSc, PhD ;   Maria Miura   ^{2, 3} , MD, PhD ;   Mizu Ohno   ^{2, 3} , MD ;   Takenori Inomata   ^{1, 2, 3, 11} , MD, MBA, PhD

¹ Department of Hospital Administration, Juntendo University Graduate School of Medicine, Tokyo, Japan

² Department of Ophthalmology, Juntendo University Graduate School of Medicine, Tokyo, Japan

³ Department of Digital Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan

⁴ Morsani College of Medicine, University of South Florida, Tampa, FL, United States

⁵ Department of Orthopedics, Juntendo University Faculty of Medicine, Tokyo, Japan

⁶ Medical Technology Innovation Center, Juntendo University, Tokyo, Japan

⁷ Graduate School of Health and Sports Science, Juntendo University, Tokyo, Japan

⁸ Department of Health Services Research, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan

⁹ Department of Ophthalmology, Toho University Omori Medical Center, Tokyo, Japan

¹⁰ Department of Ophthalmology, Tokyo Dental College Ichikawa General Hospital, Chiba, Japan

¹¹ AI Incubation Farm, Juntendo University Graduate School of Medicine, Tokyo, Japan