Addressing the Chronic Pain–Early Cognitive Decline Comorbidity Among Older Adults: Protocol for the Active Brains Remote Efficacy Trial

Ana-Maria Vranceanu   ^{1, 2} , PhD ;   Nathaniel R Choukas   ¹ , BS ;   Elizabeth A Rochon   ¹ , BA ;   Brooke Duarte   ¹ , MS ;   Malvina O Pietrzykowski   ¹ , MS ;   Katherine McDermott   ^{1, 2} , PhD ;   Julia E Hooker   ^{1, 2} , PhD ;   Ronald Kulich   ^{2, 3} , PhD ;   Yakeel T Quiroz   ^{2, 4} , PhD ;   Robert A Parker   ^{2, 5} , SCD ;   Eric A Macklin   ^{2, 5} , PhD ;   Christine Ritchie   ^{2, 6} , MSPH, MD ;   The Active Brains Project   ^{1, 2, 4, 7} ;   Ryan A Mace   ^{1, 2} , PhD

¹ Center for Health Outcomes and Interdisciplinary Research, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, United States

² Harvard Medical School, Boston, MA, United States

³ Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA, United States

⁴ Multicultural Alzheimer’s Prevention Program, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, United States

⁵ Biostatistics Center, Massachusetts General Hospital, Boston, MA, United States

⁶ Mongan Institute Center for Aging and Serious Illness and the Division of Palliative Care and Geriatric Medicine, Department of Medicine, Massachusetts General Hospital, Boston, MA, United States

⁷ Geriatric Medicine Unit, Palliative Care & Geriatric Medicine, Massachusetts General Hospital, Boston, MA, United States