Feasibility Study of Virtual Reality–Based Cognitive Behavioral Therapy for Patients With Depression: Protocol for an Open Trial and Therapeutic Intervention

Ai Ito   ¹ , MD ;   Fumikazu Hiyoshi   ^{1, 2} , MD ;   Ayako Kanie   ^{3, 4, 5} , MD, PhD ;   Azumi Maruyama   ³ , MA ;   Mari S Oba   ⁶ , PhD ;   Shinsuke Kito   ^{1, 7} , MD, PhD

¹ Department of Clinical Psychology, National Center Hospital, National Center of Neurology and Psychiatry, Kodaira-shi, Japan

² Brain Bioregulatory Science, Cooperative Graduate School, The Jikei University Graduate School of Medicine, Minato-ku, Japan

³ Jolly Good Inc, Chuo-ku, Japan

⁴ Department of Child Neropsyhchitatry, The University of Tokyo Hosoital, Bunkyo-ku, Japan

⁵ National Center for Cognitive Behavior Therapy and Research, National Center Hospital, National Center of Neurology and Psychiatry, Kodaira-shi, Japan

⁶ Department of Clinical Data Science, Clinical Research and Education Premotion Division, National Center Hospital, National Center of Neurology and Psychiatry, Kodaira-shi, Japan

⁷ Neuromodulation Therapy and Research Center, National Center Hospital, National Center of Neurology and Psychiatry, Kodaira-shi, Japan