Experimentally Induced Reductions in Alcohol Consumption and Brain, Cognitive, and Clinical Outcomes in Older Persons With and Those Without HIV Infection (30-Day Challenge Study): Protocol for a Nonrandomized Clinical Trial

Robert L Cook   ¹ , MD, MPH ;   Veronica L Richards   ^{1, 2} , PhD ;   Joseph M Gullett   ¹ , PhD ;   Brenda D G Lerner   ³ , PsyD, RN ;   Zhi Zhou   ¹ , DDS, MPH ;   Eric C Porges   ⁴ , PhD ;   Yan Wang   ¹ , PhD ;   Christopher W Kahler   ⁵ , PhD ;   Nancy P Barnett   ⁵ , PhD ;   Zhigang Li   ¹ , PhD ;   Suresh Pallikkuth   ⁶ , PhD ;   Emmanuel Thomas   ⁶ , MD, PhD ;   Allan Rodriguez   ⁶ , MD ;   Kendall J Bryant   ⁷ , PhD ;   Smita Ghare   ⁸ , PhD ;   Shirish Barve   ⁸ , PhD ;   Varan Govind   ⁶ , PhD ;   Jessy G Dévieux   ³ , PhD ;   Ronald A Cohen   ⁴ , PhD ;   The 30-Day Challenge Research Team   ⁹

¹ Southern HIV and Alcohol Research Consortium, University of Florida, Gainesville, FL, United States

² Edna Bennett Pierce Prevention Research Center, The Pennsylvania State University, University Park, PA, United States

³ Florida International University, Miami, FL, United States

⁴ Center for Cognitive Aging and Memory, University of Florida, Gainesville, FL, United States

⁵ Department of Behavioral and Social Sciences, Center for Alcohol and Addiction Studies, Brown University School of Public Health, Providence, RI, United States

⁶ Miami Center for AIDS Research, University of Miami Miller School of Medicine, Miami, FL, United States

⁷ National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, United States

⁸ Department of Medicine, University of Louisville, Louisville, KY, United States

⁹ See Acknowledgments, Gainesville, FL, United States