Adapting and Evaluating an AI-Based Chatbot Through Patient and Stakeholder Engagement to Provide Information for Different Health Conditions: Master Protocol for an Adaptive Platform Trial (the MARVIN Chatbots Study)

Yuanchao Ma   ^{1, 2, 3, 4} , MSc ;   Sofiane Achiche   ¹ , PhD ;   Marie-Pascale Pomey   ^{5, 6, 7} , MD, PhD ;   Jesseca Paquette   ⁵ , MSc ;   Nesrine Adjtoutah   ^{5, 6} , MSc ;   Serge Vicente   ^{2, 3, 8, 9} , PhD ;   Kim Engler   ^{2, 3} , PhD ;   MARVIN chatbots MARVIN chatbots Patient Expert Committee   ^{2, 10} ;   Moustafa Laymouna   ^{2, 3, 8} , MD, MSc ;   David Lessard   ^{2, 3, 4} , PhD ;   Benoît Lemire   ⁴ , MSc ;   Jamil Asselah   ¹¹ , MD ;   Rachel Therrien   ⁵ , MSc ;   Esli Osmanlliu   ^{2, 12} , MD ;   Ma'n H Zawati   ¹³ , PhD ;   Yann Joly   ¹³ , PhD ;   Bertrand Lebouché   ^{2, 3, 4, 8} , MD, PhD

¹ Department of Biomedical Engineering, Polytechnique Montréal, Montreal, QC, Canada

² Centre for Outcomes Research & Evaluation, Research Institute of the McGill University Health Centre, Montreal, QC, Canada

³ Infectious Diseases and Immunity in Global Health Program, Research Institute of McGill University Health Centre, Montreal, QC, Canada

⁴ Chronic Viral Illness Service, Division of Infectious Disease, Department of Medicine, McGill University Health Centre, Montreal, QC, Canada

⁵ Research Centre of the University of Montreal Hospital Centre, Montreal, QC, Canada

⁶ Department of Health Policy, Management and Evaluation, School of Public Health, University of Montreal, Montreal, QC, Canada

⁷ Centre of Excellence on Partnership with Patients and the Public, Montreal, QC, Canada

⁸ Department of Family Medicine, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada

⁹ Department of Mathematics and Statistics, University of Montreal, Montreal, QC, Canada

¹⁰ See Acknowledgements, Montreal, QC, Canada

¹¹ Department of Medicine, Division of Medical Oncology, McGill University Health Centre, Montreal, QC, Canada

¹² Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, QC, Canada

¹³ Centre of Genomics and Policy, McGill University, Montreal, QC, Canada