High-Throughput Computing to Detect Harmful Drug-Drug Interactions in Older Adults: Protocol for a Population-Based Cohort Study

Neda Rostamzadeh   ^{1 *} , PhD ;   Rishabh Sharma   ^{2, 3 *} , PharmD, MSc ;   Sheikh S Abdullah   ^{1, 2, 3, 4} , PhD ;   Eric McArthur   ^{2, 3} , MSc ;   Niaz Chalabianloo   ^{1, 3, 5} , PhD ;   Jessica M Sontrop   ^{2, 3, 6} , PhD ;   Matthew A Weir   ^{2, 3, 6, 7} , MD, MSc ;   Kamran Sedig   ¹ , PhD ;   Amit X Garg   ^{2, 3, 6, 7} , MD, PhD ;   Flory T Muanda   ^{2, 3, 5, 6} , MD, PhD

¹ Department of Computer Science, Western University, London, ON, Canada

² London Health Sciences Centre Research Institute, London, ON, Canada

³ ICES Ontario, London, ON, Canada

⁴ Department of Computer Science, MacEwan University, Edmonton, AB, Canada

⁵ Department of Physiology and Pharmacology, Western University, London, ON, Canada

⁶ Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada

⁷ Division of Nephrology, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada

*these authors contributed equally