Impact of the Population Medicine Multimorbidity Intervention in Xishui County (POPMIX) on People at High Risk for Chronic Obstructive Pulmonary Disease Who Experience Mental Health Symptoms: Protocol for the POPMIX-MH Cluster Randomized Controlled Trial

Yuhao Liu   ^{1 *} , BA ;   Wenjin Chen   ^{1 *} , BMed ;   Shiyu Zhang   ^{2 *} , BSc ;   Yingping Wang   ^{3 *} , BMed ;   Zhoutao Zheng   ¹ , BMed ;   Ke Huang   ^{4, 5, 6} , MD ;   Xingyao Tang   ^{4, 5} , MMSc ;   Zhong Cao   ⁷ , PhD ;   Xunliang Tong   ^{8, 9} , MD ;   Lei Tang   ¹⁰ , PhD ;   Jinghan Zhao   ⁷ , MA ;   Liu He   ¹ , BMed ;   Lirui Jiao   ¹¹ , MPH ;   Tianying Zhao   ³ , BM ;   Yingchi Luo   ³ , BMed ;   Qiande Lai   ¹² , BMed ;   Xiangqin Lyu   ¹² , BMed ;   Qiushi Chen   ¹³ , PhD ;   Aditi Bunker   ⁷ , PhD ;   Sebastian Vollmer   ¹⁴ , PhD ;   Pascal Geldsetzer   ^{15, 16} , PhD ;   Dean Jamison   ^{17, 18} , PhD ;   Till Bärnighausen   ^{1, 7, 19} , MD, ScD ;   Ting Yang   ^{4, 5, 6} , MD ;   Simiao Chen   ^{1, 6, 7} , ScD ;   Chen Wang   ^{1, 4, 5, 6} , MD ;   POPMIX Group   ²⁰

¹ School of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China

² School of Health Policy and Management, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China

³ Center for Disease Control and Prevention of Xishui County, Zunyi, China

⁴ Department of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, China

⁵ National Center for Respiratory Medicine, Beijing, China

⁶ State Key Laboratory of Respiratory Health and Multimorbidity, Beijing, China

⁷ Heidelberg Institute of Global Health, Faculty of Medicine and University Hospital, Heidelberg University, Heidelberg, Germany

⁸ Department of Pulmonary and Critical Care Medicine, Beijing Hospital, Beijing, China

⁹ Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China

¹⁰ Guizhou Medical University, Guiyang, China

¹¹ Department of Health Policy and Management, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States

¹² Department of Pulmonary and Critical Care Medicine, People’s Hospital of Xishui County, Zunyi, China

¹³ The Harold and Inge Marcus Department of Industrial and Manufacturing Engineering, Pennsylvania State University, University Park, PA, United States

¹⁴ Department of Economics and Centre for Modern Indian Studies, University of Göttingen, Göttingen, Germany

¹⁵ Division of Primary Care and Population Health, Department of Medicine, Stanford University, Stanford, CA, United States

¹⁶ Chan Zuckerberg Biohub San Francisco, San Francisco, CA, United States

¹⁷ Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, United States

¹⁸ Institute for Global Health Sciences, University of California, San Francisco, San Francisco, CA, United States

¹⁹ Department of Global and Population Health, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, United States

²⁰ see Acknowledgments

*these authors contributed equally