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Published on in Vol 15 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/91699, first published .
AI-assisted retinal screening system analyzes eye images, showing hemorrhages, exudates, and microaneurysms.

Artificial Intelligence–Assisted Screening for Patients With Diabetic Retinopathy and Age-Related Macular Degeneration in Family Medicine and Geriatric and Gerontology Care: Protocol for a Pragmatic Randomized Clinical Trial

Artificial Intelligence–Assisted Screening for Patients With Diabetic Retinopathy and Age-Related Macular Degeneration in Family Medicine and Geriatric and Gerontology Care: Protocol for a Pragmatic Randomized Clinical Trial

Bo-I Kuo   1, 2 * , MD ;   Ting-Ann Wang   3 * , PhD ;   Teresa Cheng-Chieh Chu   3 , PhD ;   Ding-Cheng Chan   4, 5, 6 , MD, PhD ;   Shao-Yi Cheng   7 , MD, MSc, DrPH ;   Chia-Ti Tsai   4, 8 , MD, PhD ;   Chu-Lin Tsai   3, 9 , MD, PhD ;   Yi-Chia Lee   3, 10 , MD, PhD ;   Chiuan-Jung Chen   11 , MSc ;   Wei-Li Chen   2 , MD, PhD ;   John Tayu Lee   12 , PhD ;   Chia-Ying Tsai   13, 14 , MD ;   Patrick Yan-Tyng Liu   15 , MD, MMS ;   Chi-Yang Chang   14, 16 , MD, PhD ;   Chia-Ter Chao   17, 18, 19 , MD, PhD ;   Jia-Horng Kao   10, 20 , MD, PhD ;   Yi-Ting Hsieh   2, 21 , MD, PhD ;   the Collaborators of AI Ophthalmology Research Group   22

1 Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan

2 Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan

3 Integrative Medical Data Center, Department of Medical Research, National Taiwan University Hospital, Taipei, Taiwan

4 Department of Geriatrics and Gerontology, National Taiwan University Hospital, Taipei, Taiwan

5 Superintendent Office, National Taiwan University Hospital Bei-Hu Branch, Taipei, Taiwan

6 Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan

7 Department of Family Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan

8 Division of Cardiology, Department of Internal Medicine and Cardiovascular Center, National Taiwan University Hospital, Taipei, Taiwan

9 Department of Emergency Medicine, National Taiwan University Hospital, Taipei, Taiwan

10 Department of Internal Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan

11 Information Technology Office, National Taiwan University Hospital, Taipei, Taiwan

12 Institute of Health Policy and Management, College of Public Health, National Taiwan University, Taipei, Taiwan

13 Department of Ophthalmology, Fu Jen Catholic University Hospital, Fu Jen Catholic University, New Taipei City, Taiwan

14 School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan

15 Division of Cardiology, Department of Internal Medicine, Min Sheng General Hospital, Taoyuan, Taiwan

16 Division of Gastroenterology and Hepatology, Department of Internal Medicine, Fu Jen Catholic University Hospital, New Taipei City, Taiwan

17 Division of Nephrology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan

18 Graduate Institute of Toxicology and Graduate Institute of Medical Education and Bioethics, National Taiwan University, Taipei, Taiwan

19 Division of Nephrology, Department of Internal Medicine, Min Sheng General Hospital, Taoyuan, Taiwan

20 Hepatitis Research Center, National Taiwan University Hospital, Taipei, Taiwan

21 Department of Ophthalmology, National Taiwan University Hospital Hsin-Chu Branch, Hsinchu, Taiwan

22 See Acknowledgments

*these authors contributed equally

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