EXpanding Treatment for Existing Neurological Disease (EXTEND): An Open-Label Phase II Clinical Trial of Hydroxyurea Treatment in Sickle Cell Anemia
EXpanding Treatment for Existing Neurological Disease (EXTEND): An Open-Label Phase II Clinical Trial of Hydroxyurea Treatment in Sickle Cell Anemia
Angela E Rankine-Mullings
1
, MBBS, MRCPCH ;
Courtney R Little
2
, RN, BSN ;
Marvin E Reid
3
, MBBS, PhD ;
Deanne P Soares
3
, MBBS, DM ;
Carolyn Taylor-Bryan
3
, MBBS, DM ;
Jennifer M Knight-Madden
1
, MBBS, PhD ;
Susan E Stuber
2
, MA ;
Asha V Badaloo
3
, PhD ;
Karen Aldred
1
, MSc ;
Margaret E Wisdom-Phipps
1
, RN, RM ;
Teresa Latham
2
, MA ;
Russell E Ware
2
, MD, PhD
1
Sickle Cell Unit, Tropical Medicine Research Institute, University of the West Indies, Kingston, Jamaica
2
Division of Hematology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, United States
3
Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Kingston, Jamaica