Safety and Efficacy of Convalescent Plasma to Treat Severe COVID-19: Protocol for the Saudi Collaborative Multicenter Phase II Study

Mohammed Albalawi   ^{1 *} , MD ;   Syed Ziauddin Ahmed Zaidi   ^{2 *} , MD ;   Nawal AlShehry   ² , MD ;   Ahmed AlAskar   ³ , MD ;   Abdul Rehman Zia Zaidi   ⁴ , MD ;   Rania Nagib Mohammed Abdallah   ⁵ , MD ;   Abdul Salam   ⁶ , DPhil ;   Ahmed AlSagheir   ⁷ , MD ;   Nour AlMozain   ⁸ , MD ;   Ghada Elgohary   ⁹ , MD ;   Khalid Batarfi   ¹⁰ , MD ;   Alia Alfaraedi   ¹¹ , MD ;   Osamah Khojah   ¹¹ , MD ;   Rehab Al-Ansari   ¹² , MD ;   Mona Alfaraj   ¹³ , MD ;   Afra Dayel   ¹⁴ , MD ;   Ahmed Al Bahrani   ¹⁵ , MD ;   Arwa Nabhan Abdelhameed   ¹⁶ , MD ;   Hind Alhumaidan   ¹⁷ , MD ;   Jawaher M Al-Otaibi   ¹⁸ , MD ;   Ghazala Radwi   ¹⁹ , MD ;   Abdulrahman Raizah   ³ , MD ;   Hind Shatry   ³ , BSc ;   Sara Alsaleh   ⁷ , MD ;   Hazzaa AlZahrani   ²⁰ , MD ;   Hani Al-Hashmi   ^{21 *} , MD

¹ Department of Internal Medicine, College of Medicine, Taibah University, Madinah, Saudi Arabia

² Department of Adult Hematology/Blood & Marrow Transplant, King Fahad Medical City, Riyadh, Saudi Arabia

³ King Abdullah International Medical Research Center, King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Riyadh, Saudi Arabia

⁴ Department of Medicine, King Fahad Medical City, Riyadh, Saudi Arabia

⁵ Department of Pulmonary and Critical Care Medicine, King Fahad Medical City, Riyadh, Saudi Arabia

⁶ Department of Epidemiology and Biostatistics, King Fahad Specialist Hospital, Dammam, Saudi Arabia

⁷ Department of Hematology and Oncology, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia

⁸ Department of Blood Bank, King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia

⁹ Oncology Center, King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia

¹⁰ Transfusion Medicine Services, Department of Pathology & Laboratory Medicine, King Abdulaziz Medical City, Riyadh, Saudi Arabia

¹¹ King Saud University, Riyadh, Saudi Arabia

¹² Department of Medicine, King Fahad Military Medical Complex, Dhahran, Saudi Arabia

¹³ Hematology Laboratory Section of Medical Laboratory Department, Qatif Central Hospital, Qatif, Saudi Arabia

¹⁴ Department of Hematopathology, King Fahad Specialist Hospital Dammam, Dammam, Saudi Arabia

¹⁵ Department of Transfusion Medicine and Stem Cell Processing, King Fahad Specialist Hospital, Dammam, Saudi Arabia

¹⁶ Department of Internal Medicine, Imam Abdulrahman Bin Faisal University, Al-Khobar, Saudi Arabia

¹⁷ Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia

¹⁸ Department of Infectious Diseases, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia

¹⁹ Department of Hematology, University of Alberta, Edmonton, ON, Canada

²⁰ Department of Hematology and Bone Marrow Transplantation Section, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia

²¹ Adult Hematology & Stem Cell Transplantation Department, Oncology Centre, King Fahad Specialist Hospital, Dammam, Saudi Arabia

*these authors contributed equally