Investigating the Mechanisms of Graded Sensorimotor Precision Training in Adults With Chronic Nonspecific Low Back Pain: Protocol for a Causal Mediation Analysis of the RESOLVE Trial

Aidan G Cashin   ^{1, 2} , PhD ;   Hopin Lee   ^{3, 4} , PhD ;   Matthew K Bagg   ^{1, 2} , BSc ;   Benedict M Wand   ⁵ , PhD ;   Edel O'Hagan   ^{1, 2} , MSc ;   Rodrigo R N Rizzo   ^{2, 6} , MSc ;   Tasha R Stanton   ⁷ , PhD ;   G Lorimer Moseley   ⁷ , PhD ;   James H McAuley   ^{2, 6} , PhD

¹ Prince of Wales Clinical School, University of New South Wales, Randwick, Australia

² Centre for Pain IMPACT, Neuroscience Research Australia, Sydney, Australia

³ Oxford Clinical Trials Research Unit and Centre for Statistics in Medicine, Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom

⁴ School of Medicine and Public Health, University of Newcastle, Newcastle, Australia

⁵ School of Physiotherapy, The University of Notre Dame, Fremantle, Australia

⁶ School of Health Sciences, University of New South Wales, Randwick, Australia

⁷ IIMPACT in Health, University of South Australia, Adelaide, Australia