Published on in Vol 11, No 7 (2022): July

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/37898, first published .
Intravenous Infusion of Autoserum-Expanded Autologous Mesenchymal Stem Cells in Patients With Chronic Brain Injury: Protocol for a Phase 2 Trial

Intravenous Infusion of Autoserum-Expanded Autologous Mesenchymal Stem Cells in Patients With Chronic Brain Injury: Protocol for a Phase 2 Trial

Intravenous Infusion of Autoserum-Expanded Autologous Mesenchymal Stem Cells in Patients With Chronic Brain Injury: Protocol for a Phase 2 Trial

Shinichi Oka 1, 2, MD, PhD;  Tomohiro Yamaki 3, MD, PhD;  Masanori Sasaki 1, 2, 4, MD, PhD;  Ryo Ukai 1, MD, PhD;  Mitsuhiro Takemura 1, MD, PhD;  Takahiro Yokoyama 1, MD;  Yuko Kataoka-Sasaki 1, 2, MD, PhD;  Rie Onodera 1, PhD;  Yoichi M Ito 5, PhD;  Shigeki Kobayashi 3, MD, PhD;  Jeffery D Kocsis 4, 6, PhD;  Yasuo Iwadate 7, MD, PhD;  Osamu Honmou 1, 2, 4, MD, PhD

1 Department of Neural Regenerative Medicine, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo , JP

2 Department of Advanced Regenerative Therapeutics, Sapporo Medical University School of Medicine , Sapporo , JP

3 Division of Neurosurgery, Rehabilitation Center for Traumatic Apallics Chiba, National Agency for Automotive Safety and Victims' Aid, Chiba , JP

4 Department of Neurology, Yale University School of Medicine , New Haven, CT, US

5 Data Science Center, Institute of Health Science Innovation for Medical Care, Hokkaido University Hospital, Sapporo , JP

6 Department of Neuroscience, Yale University School of Medicine , New Haven, CT, US

7 Department of Neurological Surgery, Chiba University Graduate School of Medicine , Chiba , JP

Corresponding Author:

  • Masanori Sasaki, MD, PhD
  • Department of Neural Regenerative Medicine
  • Research Institute for Frontier Medicine
  • Sapporo Medical University School of Medicine
  • S1W17, Chuo-ku
  • Sapporo
  • JP
  • Phone: 81 6112111
  • Email: msasaki@sapmed.ac.jp