Refocusing of Attention on Positive Events Using Monitoring-Based Feedback and Microinterventions for Patients With Chronic Musculoskeletal Pain in the PerPAIN Randomized Controlled Trial: Protocol for a Microrandomized Trial

Leonie Ader   ¹ , MSc ;   Anita Schick   ¹ , PhD ;   Martin Löffler   ² , PhD ;   Annette Löffler   ² , PhD ;   Eva Beiner   ³ , MSc ;   Wolfgang Eich   ³ , MD ;   Stephanie Vock   ³ , MSc ;   Andrei Sirazitdinov   ⁴ , MSc ;   Christopher Malone   ² , PsyD ;   Jürgen Hesser   ^{4, 5, 6, 7} , PhD ;   Michael Hopp   ⁸ , MD ;   Christian Ruckes   ⁸ , PhD ;   Herta Flor   ² , PhD, Dr hc ;   Jonas Tesarz   ³ , MD ;   Ulrich Reininghaus   ^{1, 9, 10} , PhD

¹ Department of Public Mental Health, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany

² Institute of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany

³ Department of General Internal Medicine and Psychosomatics, Heidelberg University, Heidelberg, Germany

⁴ Data Analysis and Modeling, Mannheim Institute for Intelligent Systems in Medicine, Medical School Mannheim, Heidelberg University, Mannheim, Germany

⁵ Central Institute for Scientific Computing, Heidelberg University, Heidelberg, Germany

⁶ Central Institute for Computer Engineering, Heidelberg University, Heidelberg, Germany

⁷ CZS Heidelberg Center for Model-Based AI, Heidelberg University, Heidelberg, Germany

⁸ Interdisciplinary Center for Clinical Trials, Johannes Gutenberg University Medical Center, Mainz, Germany

⁹ Centre for Epidemiology and Public Health, Health Service and Population Research Department, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, United Kingdom

¹⁰ ESRC Centre for Society and Mental Health, King´s College London, London, United Kingdom