RCTs - Pilots/Feasibility Studies (eHealth)

A Supportive Group Intervention for Caregivers to Patients Diagnosed With Glioblastoma: Protocol for the SUGRI Study

Sara Nordentoft, Rikke Guldager, Helle Pappot, Tiit Mathiesen, Anders Tolver, Karin Piil

JMIR Res Protoc 2026 (Mar 11); 15:e81948

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Digital Attention Bias in Cancer Survivors Intervention for Adolescent and Young Adult Cancer Survivors: Protocol for a Pilot Randomized Controlled Trial

Nancy Lau, Chuan Zhou, Shannon JH Hong, Homer Aalfs, Shannon Higgins, Isabel Badillo, Elizabeth McCauley, Tyler Ketterl, Eric J Chow, Jesse R Fann, Lauren C Heathcote, Tonya M Palermo

JMIR Res Protoc 2026 (Feb 25); 15:e82665

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Feasibility of a Noncontact Photoplethysmography–Based Mobile App for Noninvasive Hemoglobin Monitoring: Exploratory Observational Study

Gianvincenzo Zuccotti, Paolo Agnelli, Lucia Labati, Erika Cordaro, Davide Braghieri, Paolo Fiorina, Simona Bertoli, Cesare Celeste Federico Berra, Marina Croci, Maria Elena Malighetti, Fabrizio Losurdo, Andrea Foppiani, Loredana Bucciarelli, Marco Xodo, Alberto Battezzati, Sergio De Pasquale, Valeria Calcaterra

JMIR Form Res 2026 (Feb 19); 10:e78820

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Feasibility and Usability of an mHealth App (mLab+) to Guide Users Through HIV and Syphilis Self-Testing: Pilot Randomized Controlled Trial

Maeve Brin, Thomas F Scherr, Janejira Chaiyasit, Jianfang Liu, Maura Abbott, Robert Garofalo, Lisa M Kuhns, Tess Sky, Ian Esliker, Rebecca Schnall

JMIR Form Res 2025 (Dec 30); 9:e72955

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Smartphone App–Based Eating Behavior Monitoring and Feedback Intervention for Glucocorticoid-Induced Appetite Increase in Patients With Systemic Lupus Erythematosus: Protocol for a Pilot Randomized Controlled Trial

Takashi Yamaguchi, Nobuyuki Takahashi, Ryohei Inanaga, Ryuhei So, Hiroe Kikuchi, Hisashi Noma, Hiroyuki Sasai, Kazuro Kamada, Tomohiro Sugimoto, Hiroshi Tsushima, Takanori Ichikawa, Hirofumi Miyake, Shunichi Fujita, Keisuke Ono, Yusuke Miwa, Anna Hasegawa, Naoki Suzuki, Akira Onishi, Toshihiro Matsui, Ryu Watanabe, Yasuhiro Hasegawa, Rei Ono, Takeo Isozaki, Yuichi Ishikawa, Nobuyuki Yajima, Noriaki Kurita

JMIR Res Protoc 2025 (Dec 15); 14:e78612

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Virtual Wound Care in Australian Nursing Homes: Protocol for a Pilot and Feasibility Study

Heather Russell, Annie Banbury, Katherine Smith, Michelle Barakat-Johnson, Meredith Makeham, Georgina Luscombe

JMIR Res Protoc 2025 (Dec 02); 14:e79652

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A Digital Patient Decision Aid to Increase Sexually Transmitted Infection Testing in the Emergency Department: Protocol for a Pilot Randomized Controlled Trial of the STIckER (STI Check in the Emergency Room) Study

Jason Zucker, Delivette Castor, Marc A Probst, Talia Adler, Lisa-Pierre Tchoungui, Jaciara De Souza, Christina Franqui, Lauren Chernick

JMIR Res Protoc 2025 (Dec 02); 14:e67103

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Effects, Feasibility, and Safety of an Early Mobilization Protocol With Immersive Virtual Reality for Dyspnea in Patients With Acutely Decompensated Heart Failure: The MOVE Randomized Clinical Trial

Iasmin Borges Fraga, Larissa Gussatschenko Caballero, Carlos Eduardo Maciel Tremea, Janaína dos Santos Prates, Gabrielle Perin, Vitor Alves Guedes, Pedro Dal Lago, Eneida Rejane Rabelo-Silva

JMIR Form Res 2025 (Oct 31); 9:e80729

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Assessing the Ability of an Online Education Program to Modify Patient Expectations of Total Knee Arthroplasty Outcomes: Protocol for a Randomized Controlled Trial

Karen Ribbons, Frederick Rohan Walker, Michael Pollack, Michael Nilsson

JMIR Res Protoc 2025 (Oct 30); 14:e71898

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Advancing Knowledge of Values-Clarification Processes During Complex Decision-Making Among Older Adults With Advanced Cancer: Protocol for a Pilot Randomized Trial Using Simulated Patient-Clinician Encounters

Amy C Cole, Allison M Deal, Angela M Stover, Lisa Vizer, Fei Yu, Andy J King, Lukasz Mazur, Daniel R Richardson

JMIR Res Protoc 2025 (Oct 27); 14:e80531

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Cerina—Cognitive Behavioral Therapy–Based Mobile App for Managing Generalized Anxiety Disorder Symptoms Among University Students: Results From a Pilot Feasibility Randomized Controlled Trial

Ozlem Eylem-van Bergeijk, Tony Robinson, Matthew Manktelow, Michail Olympios, Siobhan Poulter, Prasannajeet Mane, Maria Panagioti, Joan Condell, Gerard Leavey

JMIR Mhealth Uhealth 2025 (Oct 09); 13:e70691

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A Personalized and Smartphone-Based Serious Gaming App Targeting Cognitive Impairments in Alcohol Use Disorder: Double-Blinded, Randomized Controlled Efficacy Trial Among Outpatients

Nicolaj Mistarz, Laust Vind Knudsen, Anna Mejldal, Kjeld Andersen, Anneke Goudriaan, Lotte Skøt, Tanja Maria Michel, Angelina Isabella Mellentin

JMIR Ment Health 2025 (Oct 07); 12:e67167

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An Iteratively Adapted Transdiagnostic Prevention Program for Diverse High School Settings (U-PEACE): Protocol for a Randomized Controlled Trial

Clarissa Victoria Velez, Mileini Campez-Pardo, Jennifer Mariam Canovas, Paloma Maria Pedronzo, Yeojin Amy Ahn, Chelsea Faye Dale, Sannisha K Dale, Lisa Gwynn, Amanda Jensen-Doss, Elizabeth R Pulgaron, Sara Mijares St George, Jill Ehrenreich-May

JMIR Res Protoc 2025 (Sep 24); 14:e74080

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Home-Based Exercise to Improve Functional Outcomes in Veterans With a Recently Healed Diabetic Foot Ulcer: Protocol for a Pilot Randomized Controlled Trial

Gwen L Robinson, Jake Drumheller, Alison D Lydecker, Bailey Rammling, Elizabeth A Dennis, Odessa Addison, Steven J Prior, Brock A Beamer, John D Sorkin, H David Gottlieb, Kiana Trent, Mary-Claire Roghmann

JMIR Res Protoc 2025 (Sep 23); 14:e71237

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An mHealth App–Based Social Capital Intervention (PrEP US NoW) to Improve Sexual Health and Uptake of Pre-Exposure Prophylaxis Among Young, Black, Sexual Minority Men: Protocol for Intervention Development and a Pilot Randomized Controlled Trial

Maira Sohail, Sophia A Hussen, Sarah Dougherty Sheff, Michael Mugavero, John Schneider, Lisa Hightow-Weidman, Janet M Turan, Madeline Lynam, Latesha Elopre

JMIR Res Protoc 2025 (Sep 18); 14:e66326

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Development of a Social Communication Intervention Mobile App for Adolescents With Autism Spectrum Disorder and Social Communication Disorder: Protocol for a Pilot Randomized Clinical Trial

Enn Young Lee, SungJa Cho, Ran Ju, Hyunjae Kim, Tae Young Choi, Jae Hyun Yoo, Yoo-Sook Joung

JMIR Res Protoc 2025 (Sep 09); 14:e66419

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Comparison of Telehealth and Onsite Supervised Maintenance Exercise Programs for Adults With Chronic Lung Disease: Protocol for a Pilot Randomized Feasibility Trial

Rania Karim, Lesley Smith, Jane Baldwin, Rebecca Pham, Hyun Jung Kim, Lauren Miccile, Michael Sullivan, Shweta Gore

JMIR Res Protoc 2025 (Aug 25); 14:e71039

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A Work-Based, Fully Remote, and Peer-Supported Exercise Snack Behavior Change Intervention (MOV’D): Protocol for a Randomized Controlled Pilot Trial

Ashley Monteiro, Jessie Moore, Rocky Aikens, James J Gross, Dan Schwartz, Mike Baiocchi, Judith J Prochaska, Marily Oppezzo

JMIR Res Protoc 2025 (Aug 07); 14:e64455

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Gamification of Incentive Spirometry in Trauma Patients: Protocol for a Prospective, Observational Feasibility Study

Areen Al-Dhoon, Arthur Grimes, Carma Goldstein, Peter Spronk, R Shayn Martin, Aarti Sarwal

JMIR Res Protoc 2025 (Aug 01); 14:e75871

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Mobile Health Technology for Personalized Tobacco Cessation Support Among Cancer Survivors and Caregivers in Laos (Project SurvLaos): Protocol for a Pilot Randomized Controlled Trial

Phayvanh Keopaseuth, Phonepadith Xangsayarath, Shweta Kulkarni, Khatthanaphone Phandouangsy, Chanthavy Soulaphy, Phetsamone Alounlungsy, Vangnakhone Dittaphong, Dalouny Xayavong, Champadeng Vongdala, Latsamy Siengsounthone, Michael Businelle, Summer G Frank-Pearce, Damon J Vidrine, Jennifer I Vidrine, Thanh Cong Bui

JMIR Res Protoc 2025 (Jul 30); 14:e66517

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