Erlotinib or Gefitinib for Treating Advanced Epidermal Growth Factor Receptor Mutation–Positive Lung Cancer in Aotearoa New Zealand: Protocol for a National Whole-of-Patient-Population Retrospective Cohort Study and Results of a Validation Substudy

Phyu Sin Aye   ¹ ;   Joanne Barnes   ² ;   George Laking   ³ ;   Laird Cameron   ⁴ ;   Malcolm Anderson   ⁵ ;   Brendan Luey   ⁶ ;   Stephen Delany   ⁷ ;   Dean Harris   ⁸ ;   Blair McLaren   ⁹ ;   Elliott Brenman   ¹⁰ ;   Jayden Wong   ¹¹ ;   Ross Lawrenson   ¹² ;   Michael Arendse   ¹³ ;   Sandar Tin Tin   ¹⁴ ;   Mark Elwood   ¹⁴ ;   Philip Hope   ¹⁵ ;   Mark James McKeage   ^{1, 4, 16}

¹ Department of Pharmacology and Clinical Pharmacology, University of Auckland, Auckland, New Zealand

² School of Pharmacy, University of Auckland, Auckland, New Zealand

³ Te Aka Mātauranga Matepukupuku Centre for Cancer Research, University of Auckland, Auckland, New Zealand

⁴ Department of Medical Oncology, Te Pūriri o Te Ora Regional Cancer and Blood Service, Te Whatu Ora Health New Zealand, Auckland City Hospital, Auckland, New Zealand

⁵ Department of Medical Oncology, Te Whatu Ora Health New Zealand Te Pae Hauuora o Ruahine o Tararua, Palmerston North Hospital, Palmerston North, New Zealand

⁶ Wellington Blood and Cancer Centre, Te Whatu Ora Health New Zealand Capital, Coast and Hutt Valley, Wellington Hospital, Wellington, New Zealand

⁷ Department of Oncology, Te Whatu Ora Health New Zealand Nelson Marlborough, Nelson Hospital, Nelson, New Zealand

⁸ Oncology Service, Te Whatu Ora – Waitaha Canterbury, Christchurch Hospital, Christchurch, New Zealand

⁹ Southern Blood and Cancer Service, Te Whatu Ora Southern, Dunedin Hospital, Dunedin, New Zealand

¹⁰ Cancer and Haematology Services, Te Whatu Ora Health New Zealand Haora a Toi Bay of Plenty, Tauranga Hospital, Tauranga, New Zealand

¹¹ Cancer Services, Te Whatu Ora Health New Zealand Waikato, Waikato Hospital, Hamilton, New Zealand

¹² Medical Research Centre, University of Waikato, Hamilton, New Zealand

¹³ Department of Pathology, Te Whatu Ora Health New Zealand Waikato, Waikato Hospital, Hamilton, New Zealand

¹⁴ Department of Epidemiology and Biostatistics, University of Auckland, Auckland, New Zealand

¹⁵ Lung Foundation New Zealand, Manukau, Auckland, New Zealand

¹⁶ Auckland Cancer Society Research Centre, University of Auckland, Auckland, New Zealand