The COSMOS Registry of CytoSorb Hemoadsorption Therapy in Critically Ill Patients: Protocol for an International, Prospective Registry

Fabio Silvio Taccone   ¹ , MD ;   Frank Martin Brunkhorst   ² , MD ;   Gabriella Bottari   ³ , MD ;   Jorge Hidalgo   ⁴ , MD ;   Andreas Kribben   ⁵ , MD ;   Jean-Louis Teboul   ⁶ , MD ;   Dana Tomescu   ⁷ , MD ;   Teresa Klaus   ⁸ , MD ;   Joerg Scheier   ⁸ , MD ;   Efthymios Deliargyris   ⁹ , MD ;   Ricard Ferrer   ¹⁰ , MD

¹ Department of Intensive Care, Hôpital Universitaire de Bruxelles (HUB), Université Libre de Bruxelles (ULB), Brussels, Belgium

² Integriertes Forschungs- und Behandlungszentrum (IFB) Sepsis und Sepsisfolgen, Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Jena, Jena, Germany

³ Pediatric Intensive Care Unit, Children Hospital Bambino Gesù, IRCCS, Rome, Italy

⁴ General Intensive Care Unit and COVID-19 Unit, Belize Healthcare Partners, Belize City, Belize

⁵ Klinik für Nephrologie, University Duisburg-Essen, University Hospital Essen, Essen, Germany

⁶ Paris-Saclay Medical School, Paris-Saclay University, Le Kremlin-Bicêtre, Paris, France

⁷ Department of Anesthesiology and Critical Care, “Carol Davila, Bucharest, Romania

⁸ CytoSorbents Europe GmbH, Berlin, Germany

⁹ CytoSorbents Corporation and CytoSorbents Medical Inc., Princeton, NJ, United States

¹⁰ Intensive Care Department, Vall d'Hebron University Hospital, Shock, Organ Dysfunction and Resuscitation Research Group (SODIR), Barcelona, Spain