Quantification of Urinary Exosomal Prostate-Specific Antigen for the Diagnosis of Prostate Cancer Using Clinical Laboratory–Based Techniques: Protocol for a Case-Control Study

Guorong Li   ¹ , MD, PhD ;   Yannick Tholance   ² , PharmD, PhD ;   Nora Mallouk   ³ , PhD ;   Louis Waeckel   ^{1, 4} , PharmD, PhD ;   Pascale Flandrin   ⁵ , PharmD, PhD ;   Bruno Bali   ¹ , MD ;   Lionel Badet   ^{1 *} , MD ;   Pierre Cornillon   ^{6 *} , MD

¹ Department of Urology, North Hospital, CHU Saint-Etienne, Saint-Etienne, France

² Laboratory of Biochemistry, North Hospital, CHU Saint-Etienne, Saint-Etienne, France

³ Center of Electronic Microscopy, CMES, Faculty of Medicine, University of Jean Monnet, Saint-Etienne, France

⁴ Laboratory of Flow Cytometry, Immunology Laboratory, North Hospital, CHU Saint-Etienne, Saint-Etienne, France

⁵ Laboratory of Molecular Biology, North Hospital, CHU Saint-Etienne, Saint-Etienne, France

⁶ Department of Medical Oncology, North Hospital, CHU Saint-Etienne, Saint-Etienne, France

*these authors contributed equally