IL-6/GP130/JAK/STAT3 Pathway Activation in Pancreatic Ductal Adenocarcinoma and Its Association With Clinical Features: Protocol for a Retrospective Cross-Sectional Study

Claudia Mellenthin   ^{1, 2 *} , MD ;   Fabien Schaller   ^{1, 2 *} , MMed ;   Lucie Vignot   ³ , MD ;   Sarah Peisl   ⁴ , MD ;   Rita Vesce   ⁵ , MMed ;   Irene Esposito   ⁵ , Prof Dr Med ;   Carmen Gonelle-Gispert   ² , PhD ;   Cornelia Schneider   ^{6, 7} , PhD ;   Michel Adamina   ^{2, 4} , MSc, EMBA, Prof Dr Med ;   Leo Hans Bühler   ^{1, 2} , Prof Dr Med

¹ Department of Surgery, Hospital Fribourg, Fribourg, Switzerland

² Department of Medical and Surgical Specialties, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland

³ Department of Oncology, Hospital Fribourg, Fribourg, Switzerland

⁴ Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland

⁵ Institute of Pathology, Düsseldorf University Hospital, Düsseldorf, Germany

⁶ Clinical Pharmacy and Epidemiology, Department of Pharmaceutical Sciences, University of Basel, Basel, Basel-City, Switzerland

⁷ Basel Pharmacoepidemiology Unit, University Hospital Basel, Basel, Basel-City, Switzerland

*these authors contributed equally