Published on in Vol 14 (2025)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/77681, first published .
The White Matter Hyperintensity Shape and Brain Clearance (WHIMAS) Study for Identification of Novel 7T Magnetic Resonance Imaging Markers of Cerebral Small Vessel Disease: Protocol for a Cross-Sectional Study

The White Matter Hyperintensity Shape and Brain Clearance (WHIMAS) Study for Identification of Novel 7T Magnetic Resonance Imaging Markers of Cerebral Small Vessel Disease: Protocol for a Cross-Sectional Study

The White Matter Hyperintensity Shape and Brain Clearance (WHIMAS) Study for Identification of Novel 7T Magnetic Resonance Imaging Markers of Cerebral Small Vessel Disease: Protocol for a Cross-Sectional Study

Jasmin Annica Kuhn-Keller   1, 2 , PhD ;   Ingmar Eiling   1, 2 , MSc ;   Lydiane Hirschler   1, 2 , PhD ;   Lena Václavů   1, 2 , PhD ;   Marie-Noëlle Witjes-Ané   3, 4 , PhD ;   Marjolein Wijngaarden   3, 5 , MD, PhD ;   Martijn Nagtegaal   1, 2 , PhD ;   Ece Ercan   1, 2 , PhD ;   Nathaly Rius Ottenheim   4 , MD, PhD ;   Marjan van der Elst   3, 5 , RN ;   Evelien Sohl   6 , MD ;   Mark A van Buchem   2 , MD, PhD ;   Simon Mooijaart   3, 5 , MD, PhD ;   Matthias JP van Osch   1, 2 , PhD ;   Jeroen de Bresser   2 , MD, PhD

1 CJ Gorter MRI Center, Department of Radiology, Leiden University Medical Center, Leiden, South Holland, The Netherlands

2 Department of Radiology, Leiden University Medical Center, Leiden, South Holland, The Netherlands

3 Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, South Holland, The Netherlands

4 Department of Psychiatry, Leiden University Medical Center, Leiden, South Holland, The Netherlands

5 Center for Medicine for Older People, Leiden University Medical Center, Leiden, South Holland, The Netherlands

6 Department of Geriatrics, Alrijne Hospital Leiden, Leiden, South Holland, The Netherlands

Corresponding Author:

  • Jeroen de Bresser, MD, PhD
  • Department of Radiology
  • Leiden University Medical Center
  • Albinusdreef 2
  • Leiden, South Holland 2333 ZA
  • The Netherlands
  • Phone: 31 715264376
  • Email: J.H.J.M.de_Bresser@lumc.nl