Effects of Time-Restricted Eating on Ketone Metabolism and Immunoregulation in Premenopausal Women: Protocol for a Pilot, Prospective, Single-Arm Dietary Intervention Study

Geethika P Thota   ^{1 *} , MD ;   Natalie A Macheret   ^{1 *} , BS ;   Sophia B Glaros   ¹ , BS ;   Ila N Kacker   ^{1 *} , BA ;   Samson L Cantor   ^{1 *} , BA ;   Lilian Mabundo   ^{1 *} , RN, MSN, CDCES ;   Noemi Malandrino   ^{1 *} , MD, PhD ;   Kong Y Chen   ^{1 *} , PhD ;   Amber B Courville   ^{1 *} , RD, PhD ;   Sara Turner   ^{1 *} , MPH, RD ;   Shanna Yang   ^{1 *} , MPH, RD ;   Andrea Krenek   ^{1 *} , RD, PhD ;   Thomas C Recupero   ^{2 *} , BA ;   Rachael J Klein   ^{2 *} , MD ;   Kim Han   ^{2 *} , PhD ;   Patrycja Puchalska   ^{3 *} , PhD ;   Peter Crawford   ^{3 *} , MD, PhD ;   Michael N Sack   ^{2 *} , MD, PhD ;   Stephanie T Chung   ^{1 *} , MBBS

¹ Diabetes Endocrinology and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Rockville, MD, United States

² Laboratory of Mitochondrial Biology and Metabolism, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, United States

³ Clinical and Translational Science Institute, University of Minnesota, Minneapolis, MN, United States

*these authors contributed equally