Optimizing Antiemetic Support in Anthracycline-Based Chemotherapy for Early Breast Cancer: Protocol for a Prospective Observational Study of Four-Drug Antiemetic Therapy Including Fosnetupitant and Olanzapine

Ayako Higuchi   ¹ , MSc ;   Yumiko Koi   ² , MD, PhD ;   Tomoaki Eto   ^{1, 3} , MSc ;   Yuka Maeda   ¹ , BSc ;   Wakako Tajiri   ² , MD ;   Junji Kawasaki   ² , MD ;   Sayuri Akiyoshi   ² , MD, PhD ;   Hideki Ijichi   ² , MD, PhD ;   Yoshiaki Nakamura   ² , MD, PhD ;   Chinami Koga   ² , MD ;   Mototsugu Shimokawa   ⁴ , PhD ;   Hiroaki Shimizu   ^{1, 5} , BSc ;   Toshihiro Matsumoto   ¹ , BSc ;   Eriko Tokunaga   ² , MD, PhD

¹ Department of Pharmacy, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan

² Department of Breast Oncology, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan

³ Department of Pharmacy, National Hospital Organization Kokura Medical Center, Kitakyushu, Japan

⁴ Department of Biostatistics, Yamaguchi University, Yamaguchi, Japan

⁵ Department of Pharmacy, National Sanatorium Kikuchi Keifuen, Koshi, Japan