Recent Articles
![Gender Inequalities of Health and Quality of Life in Informal Caregivers in Spain: Protocol for the Longitudinal and Multicenter CUIDAR-SE Study Article Thumbnail](https://asset.jmir.pub/assets/4b8a750e855156dc3a0d4e183fca0ff3.png 480w,https://asset.jmir.pub/assets/4b8a750e855156dc3a0d4e183fca0ff3.png 960w,https://asset.jmir.pub/assets/4b8a750e855156dc3a0d4e183fca0ff3.png 1920w,https://asset.jmir.pub/assets/4b8a750e855156dc3a0d4e183fca0ff3.png 2500w)
The aging population and increased disability prevalence in Spain have heightened the demand for long-term care. Informal caregiving, primarily performed by women, plays a crucial role in this scenario. This protocol outlines the CUIDAR-SE study, focusing on the gender-specific impact of informal caregiving on health and quality of life among caregivers in Andalusia and the Basque Country from 2013 to 2024.
![Body Composition and Energy Expenditure in Youth With Spina Bifida: Protocol for a Multisite, Cross-Sectional Study Article Thumbnail](https://asset.jmir.pub/assets/5a9101778e6bb7f1556d67824e2de7c1.png 480w,https://asset.jmir.pub/assets/5a9101778e6bb7f1556d67824e2de7c1.png 960w,https://asset.jmir.pub/assets/5a9101778e6bb7f1556d67824e2de7c1.png 1920w,https://asset.jmir.pub/assets/5a9101778e6bb7f1556d67824e2de7c1.png 2500w)
Obesity prevalence in youth with spina bifida is higher than in their typically developing peers. Obesity is associated with lifelong medical, psychological, and economic burdens. Successful prevention or treatment of obesity in individuals with spina bifida is compromised by (1) the lack of valid and reliable methods to identify body fat in a clinical setting and (2) limited data on energy expenditure that are necessary to provide daily caloric recommendations.
![Erlotinib or Gefitinib for Treating Advanced Epidermal Growth Factor Receptor Mutation–Positive Lung Cancer in Aotearoa New Zealand: Protocol for a National Whole-of-Patient-Population Retrospective Cohort Study and Results of a Validation Substudy Article Thumbnail](https://asset.jmir.pub/assets/f14ad01c9bcd9e89680b52a122490ca3.png 480w,https://asset.jmir.pub/assets/f14ad01c9bcd9e89680b52a122490ca3.png 960w,https://asset.jmir.pub/assets/f14ad01c9bcd9e89680b52a122490ca3.png 1920w,https://asset.jmir.pub/assets/f14ad01c9bcd9e89680b52a122490ca3.png 2500w)
![Assessment of the Feasibility of Objective Parameters as Primary End Points for Patients Affected by Knee Osteoarthritis: Protocol for a Pilot, Open Noncontrolled Trial (:SMILE:) Article Thumbnail](https://asset.jmir.pub/assets/259c9d9410600c31ba7ce57327aeb67e.png 480w,https://asset.jmir.pub/assets/259c9d9410600c31ba7ce57327aeb67e.png 960w,https://asset.jmir.pub/assets/259c9d9410600c31ba7ce57327aeb67e.png 1920w,https://asset.jmir.pub/assets/259c9d9410600c31ba7ce57327aeb67e.png 2500w)
Osteoarthritis (OA) is a disabling condition that affects more than one-third of people older than 65 years. Currently, 80% of these patients report movement limitations, 20% are unable to perform major activities of daily living, and approximately 11% require personal care. In 2014, the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) recommended, as the first step in the pharmacological treatment of knee osteoarthritis, a background therapy with chronic symptomatic slow-acting osteoarthritic drugs such as glucosamine sulfate, chondroitin sulfate, and hyaluronic acid. The latter has been extensively evaluated in clinical trials as intra-articular and oral administration. Recent reviews have shown that studies on oral hyaluronic acid generally measure symptoms using only subjective parameters, such as visual analog scales or quality of life questionnaires. As a result, objective measures are lacking, and data validity is generally impaired.
![mHealth-Based Just-in-Time Adaptive Intervention to Improve the Physical Activity Levels of Individuals With Spinal Cord Injury: Protocol for a Randomized Controlled Trial Article Thumbnail](https://asset.jmir.pub/assets/d0daf0e72af5ab3ddefafd708657c14d.png 480w,https://asset.jmir.pub/assets/d0daf0e72af5ab3ddefafd708657c14d.png 960w,https://asset.jmir.pub/assets/d0daf0e72af5ab3ddefafd708657c14d.png 1920w,https://asset.jmir.pub/assets/d0daf0e72af5ab3ddefafd708657c14d.png 2500w)
The lack of regular physical activity (PA) in individuals with spinal cord injury (SCI) in the United States is an ongoing health crisis. Regular PA and exercise-based interventions have been linked with improved outcomes and healthier lifestyles among those with SCI. Providing people with an accurate estimate of their everyday PA level can promote PA. Furthermore, PA tracking can be combined with mobile health technology such as smartphones and smartwatches to provide a just-in-time adaptive intervention (JITAI) for individuals with SCI as they go about everyday life. A JITAI can prompt an individual to set a PA goal or provide feedback about their PA levels.
![Assessing Functional Capacity in Directly and Remotely Monitored Home-Based Settings in Individuals With Chronic Respiratory Diseases: Protocol for a Multinational Validation Study Article Thumbnail](https://asset.jmir.pub/assets/cf5634a4c62b4e4fbd8fbb09b18d7964.png 480w,https://asset.jmir.pub/assets/cf5634a4c62b4e4fbd8fbb09b18d7964.png 960w,https://asset.jmir.pub/assets/cf5634a4c62b4e4fbd8fbb09b18d7964.png 1920w,https://asset.jmir.pub/assets/cf5634a4c62b4e4fbd8fbb09b18d7964.png 2500w)
Pulmonary rehabilitation is widely recommended to improve functional status and as secondary and tertiary prevention in individuals with chronic pulmonary diseases. Unfortunately, access to timely and appropriate rehabilitation remains limited. To help close this inaccessibility gap, telerehabilitation has been proposed. However, exercise testing is necessary for effective and safe exercise prescription. Current gold-standard tests, such as maximal cardiopulmonary exercise testing (CPET) and the 6-minute walk test (6MWT), are poorly adapted to home-based or telerehabilitation settings. This was an obstacle to the continuity of services during the COVID-19 pandemic. It is essential to validate tests adapted to these new realities, such as the 6-minute stepper test (6MST). This test, strongly inspired by 6MWT, consists of taking as many steps as possible on a “stepper” for 6 minutes.
![Effects of a Patient Portal Intervention to Address Diabetes Care Gaps: Protocol for a Pragmatic Randomized Controlled Trial Article Thumbnail](https://asset.jmir.pub/assets/0a03b4b3d7d12772631384b627177b09.png 480w,https://asset.jmir.pub/assets/0a03b4b3d7d12772631384b627177b09.png 960w,https://asset.jmir.pub/assets/0a03b4b3d7d12772631384b627177b09.png 1920w,https://asset.jmir.pub/assets/0a03b4b3d7d12772631384b627177b09.png 2500w)
Despite the potential to significantly reduce complications, many patients do not consistently receive diabetes preventive care. Our research team recently applied user-centered design sprint methodology to develop a patient portal intervention empowering patients to address selected diabetes care gaps (eg, no diabetes eye examination in last 12 months).
![Detecting Algorithmic Errors and Patient Harms for AI-Enabled Medical Devices in Randomized Controlled Trials: Protocol for a Systematic Review Article Thumbnail](https://asset.jmir.pub/assets/34583976564c226b36605424a2bbb555.png 480w,https://asset.jmir.pub/assets/34583976564c226b36605424a2bbb555.png 960w,https://asset.jmir.pub/assets/34583976564c226b36605424a2bbb555.png 1920w,https://asset.jmir.pub/assets/34583976564c226b36605424a2bbb555.png 2500w)
Artificial intelligence (AI) medical devices have the potential to transform existing clinical workflows and ultimately improve patient outcomes. AI medical devices have shown potential for a range of clinical tasks such as diagnostics, prognostics, and therapeutic decision-making such as drug dosing. There is, however, an urgent need to ensure that these technologies remain safe for all populations. Recent literature demonstrates the need for rigorous performance error analysis to identify issues such as algorithmic encoding of spurious correlations (eg, protected characteristics) or specific failure modes that may lead to patient harm. Guidelines for reporting on studies that evaluate AI medical devices require the mention of performance error analysis; however, there is still a lack of understanding around how performance errors should be analyzed in clinical studies, and what harms authors should aim to detect and report.
![Effects of Sound Interventions on the Mental Stress Response in Adults: Protocol for a Scoping Review Article Thumbnail](https://asset.jmir.pub/assets/197b0f85c7fb10a5327d4a0ff2914ce1.png 480w,https://asset.jmir.pub/assets/197b0f85c7fb10a5327d4a0ff2914ce1.png 960w,https://asset.jmir.pub/assets/197b0f85c7fb10a5327d4a0ff2914ce1.png 1920w,https://asset.jmir.pub/assets/197b0f85c7fb10a5327d4a0ff2914ce1.png 2500w)
Sound therapy methods have seen a surge in popularity, with a predominant focus on music among all types of sound stimulation. There is substantial evidence documenting the integrative impact of music therapy on psycho-emotional and physiological outcomes, rendering it beneficial for addressing stress-related conditions such as pain syndromes, depression, and anxiety. Despite these advancements, the therapeutic aspects of sound, as well as the mechanisms underlying its efficacy, remain incompletely understood. Existing research on music as a holistic cultural phenomenon often overlooks crucial aspects of sound therapy mechanisms, particularly those related to speech acoustics or the so-called “music of speech.”
![Experiences of Governments and Public Health Agencies Regarding Crisis Communication During the COVID-19 Pandemic in the Digital Age: Protocol for a Systematic Review of Qualitative Studies Article Thumbnail](https://asset.jmir.pub/assets/4ca88158af43539d74f306b93bb724a6.png 480w,https://asset.jmir.pub/assets/4ca88158af43539d74f306b93bb724a6.png 960w,https://asset.jmir.pub/assets/4ca88158af43539d74f306b93bb724a6.png 1920w,https://asset.jmir.pub/assets/4ca88158af43539d74f306b93bb724a6.png 2500w)
Governments and public health agencies worldwide experienced difficulties with social media–mediated infodemics on the internet during the COVID-19 pandemic. Existing public health crisis communication strategies need to be updated. However, crisis communication experiences of governments and public health agencies worldwide during the COVID-19 pandemic have not been systematically compiled, necessitating updated crisis communication strategies.
![Effects of Lifestyle Interventions on Cardiovascular Disease Risk and Risk Factors Among Individuals at High Risk for Type 2 Diabetes: Protocol for a Systematic Review and Meta-Analysis of Randomized Controlled Trials Article Thumbnail](https://asset.jmir.pub/assets/72ddf0f8fd97af0a958fbf7c9416ce64.png 480w,https://asset.jmir.pub/assets/72ddf0f8fd97af0a958fbf7c9416ce64.png 960w,https://asset.jmir.pub/assets/72ddf0f8fd97af0a958fbf7c9416ce64.png 1920w,https://asset.jmir.pub/assets/72ddf0f8fd97af0a958fbf7c9416ce64.png 2500w)
Individuals at high risk for type 2 diabetes are also at an increased risk for developing cardiovascular disease (CVD). Although there are separate trials examining the effects of lifestyle interventions on absolute CVD risk among people at high risk for type 2 diabetes, a comprehensive evidence synthesis of these trials is lacking.
![Social Factors Associated With Nutrition Risk in Community-Dwelling Older Adults in High-Income Countries: Protocol for a Scoping Review Article Thumbnail](https://asset.jmir.pub/assets/7d96956be1ab162b512ca28a98da35c3.png 480w,https://asset.jmir.pub/assets/7d96956be1ab162b512ca28a98da35c3.png 960w,https://asset.jmir.pub/assets/7d96956be1ab162b512ca28a98da35c3.png 1920w,https://asset.jmir.pub/assets/7d96956be1ab162b512ca28a98da35c3.png 2500w)
In high-income countries (HICs), between 65% and 70% of community-dwelling adults aged 65 and older are at high nutrition risk. Nutrition risk is the risk of poor dietary intake and nutritional status. Consequences of high nutrition risk include frailty, hospitalization, death, and reduced quality of life. Social factors (such as social support and commensality) are known to influence eating behavior in later life; however, to the authors’ knowledge, no reviews have been conducted examining how these social factors are associated with nutrition risk specifically.
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