Normothermic Versus Hypothermic Cardiopulmonary Bypass in Children Undergoing Open Heart Surgery (Thermic-2): Study Protocol for a Randomized Controlled Trial

Sarah Baos   ¹ , PhD ;   Karen Sheehan   ² , RGN, RSCN, MSc ;   Lucy Culliford   ¹ , PhD ;   Katie Pike   ¹ , MSc ;   Lucy Ellis   ¹ , MRes ;   Andrew J Parry   ^{2, 3} , DM (Oxon),FRCS (CTh) (Eng) ;   Serban Stoica   ² , FRCS (CTh), MD ;   Mohamed T Ghorbel   ³ , PhD ;   Massimo Caputo   ² , MD ;   Chris A Rogers   ¹ , PhD

¹ Clinical Trials and Evaluation Unit, School of Clinical Sciences, University of Bristol, Bristol, United Kingdom

² Bristol Royal Hospital for Children, Division of Women and Children, University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom

³ Bristol Heart Institute, University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom