This paper is in the following e-collection/theme issue:

RCTs - Protocols/Proposals (non-eHealth) (311)

Published on in Vol 8, No 2 (2019): February

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/11441, first published .
The Safety, Tolerability, and Effects on the Systemic Inflammatory Response and Renal Function of the Human Chorionic Gonadotropin Hormone-Derivative EA-230 Following On-Pump Cardiac Surgery (The EASI Study): Protocol for a Randomized, Double-Blind, Placebo-Controlled Phase 2 Study

The Safety, Tolerability, and Effects on the Systemic Inflammatory Response and Renal Function of the Human Chorionic Gonadotropin Hormone-Derivative EA-230 Following On-Pump Cardiac Surgery (The EASI Study): Protocol for a Randomized, Double-Blind, Placebo-Controlled Phase 2 Study

The Safety, Tolerability, and Effects on the Systemic Inflammatory Response and Renal Function of the Human Chorionic Gonadotropin Hormone-Derivative EA-230 Following On-Pump Cardiac Surgery (The EASI Study): Protocol for a Randomized, Double-Blind, Placebo-Controlled Phase 2 Study

Authors of this article:

Roger van Groenendael1, 2, 3 Author Orcid Image ;   Remi Beunders1, 2 Author Orcid Image ;   Jan Hofland3 Author Orcid Image ;   Wim J Morshuis4 Author Orcid Image ;   Matthijs Kox1, 2 Author Orcid Image ;   Lucas T van Eijk3 Author Orcid Image ;   Peter Pickkers1, 2 Author Orcid Image
Article Authors Cited by (9) Tweetations (1) Metrics

Journals

  1. van Groenendael R, Beunders R, Kox M, van Eijk L, Pickkers P. The Human Chorionic Gonadotropin Derivate EA-230 Modulates the Immune Response and Exerts Renal Protective Properties: Therapeutic Potential in Humans. Seminars in Nephrology 2019;39(5):496 View
  2. van Groenendael R, Aarnoutse R, Kox M, van Eijk L, Pickkers P. Pharmacokinetics, safety and tolerability of the novel β‐hCG derived immunomodulatory compound, EA‐230. British Journal of Clinical Pharmacology 2019;85(7):1572 View
  3. van Groenendael R, Kox M, Leijte G, Koeneman B, Gerretsen J, van Eijk L, Pickkers P. A randomized double‐blind, placebo‐controlled clinical phase IIa trial on safety, immunomodulatory effects and pharmacokinetics of EA‐230 during experimental human endotoxaemia. British Journal of Clinical Pharmacology 2019;85(7):1559 View
  4. van Groenendael R, Beunders R, Hemelaar P, Hofland J, Morshuis W, van der Hoeven J, Gerretsen J, Wensvoort G, Kooistra E, Claassen W, Waanders D, Lamberts M, Buijsse L, Kox M, van Eijk L, Pickkers P. Safety and Efficacy of Human Chorionic Gonadotropin Hormone-Derivative EA-230 in Cardiac Surgery Patients: A Randomized Double-Blind Placebo-Controlled Study. Critical Care Medicine 2021;49(5):790 View
  5. Côté J, Murray P, Rosner M. New drugs for acute kidney injury. Current Opinion in Critical Care 2020;26(6):525 View
  6. Habes Q, Kant N, Beunders R, van Groenendael R, Gerretsen J, Kox M, Pickkers P. Relationships Between Systemic Inflammation, Intestinal Damage and Postoperative Organ Dysfunction in Adults Undergoing Low-Risk Cardiac Surgery. Heart, Lung and Circulation 2023;32(3):395 View
  7. Timganova V, Bochkova M, Shardina K, Uzhviyuk S, Gutina E, Rayev M, Lyubimov A, Zamorina S. Effect of short PSG peptide fragments on the cytokine profile in Wistar rats during allogeneic transplantation <i>in vivo</i>. Medical Immunology (Russia) 2022;24(3):491 View
  8. Ko C, Zang S, Zhou Y, Zhong Z, Yang C. Nanocarriers for effective delivery: modulation of innate immunity for the management of infections and the associated complications. Journal of Nanobiotechnology 2022;20(1) View
  9. Beunders R, Donato L, van Groenendael R, Arlt B, Carvalho-Wodarz C, Schulte J, Coolen A, Lieske J, Meeusen J, Jaffe A, Pickkers P. Assessing GFR With Proenkephalin. Kidney International Reports 2023;8(11):2345 View