This paper is in the following e-collection/theme issue:

RCTs - Protocols/Proposals (non-eHealth) (421) COVID-19 Vaccination (181) Protocols for Public Health Research and Surveillance (115) Outbreak and Pandemic Preparedness and Management (1834) Innovations in Clinical Trials and Research Data Management (130) Public (e)Health, Digital Epidemiology and Public Health Informatics (1040)

Published on in Vol 15 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/80858, first published .
Real-World Effectiveness and Noninferiority Evaluation and Comparison of Messenger RNA–Based and Protein-Based COVID-19 Vaccines: Protocol for the BEEHIVE Randomized Study With a Hybrid Effectiveness Design

Real-World Effectiveness and Noninferiority Evaluation and Comparison of Messenger RNA–Based and Protein-Based COVID-19 Vaccines: Protocol for the BEEHIVE Randomized Study With a Hybrid Effectiveness Design

Real-World Effectiveness and Noninferiority Evaluation and Comparison of Messenger RNA–Based and Protein-Based COVID-19 Vaccines: Protocol for the BEEHIVE Randomized Study With a Hybrid Effectiveness Design

Authors of this article:

Sarang K Yoon1 Author Orcid Image ;   German L Ellsworth2 Author Orcid Image ;   Steph Battan-Wraith3 Author Orcid Image ;   Andrew L Phillips1 Author Orcid Image ;   Rebecca V Fink3 Author Orcid Image ;   Joshua Griffin4 Author Orcid Image ;   Elizabeth A K Rowley3 Author Orcid Image ;   Jacob McKell5 Author Orcid Image ;   Ashley S Smith3 Author Orcid Image ;   Riley Campbell1 Author Orcid Image ;   Jesse Williams1 Author Orcid Image ;   Sarah W Ball3 Author Orcid Image ;   Hongwei Zhao2 Author Orcid Image ;   Brandy Warren6 Author Orcid Image ;   Matthew D Rousculp6 Author Orcid Image ;   Matthew S Thiese2 Author Orcid Image
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