Engaging Caregivers and Providers of Children With Sickle Cell Anemia in Shared Decision Making for Hydroxyurea: Protocol for a Multicenter Randomized Controlled Trial

Anna M Hood   ¹ , BA, MA, PhD ;   Heather Strong   ² , PhD ;   Cara Nwankwo   ³ , BA ;   Yolanda Johnson   ² , MS ;   James Peugh   ² , PhD ;   Constance A Mara   ² , PhD ;   Lisa M Shook   ^{4, 5} , DHPE, MCHES ;   William B Brinkman   ^{4, 6} , MD ;   Francis J Real   ^{4, 6} , MD ;   Melissa D Klein   ^{4, 6} , MD ;   Rogelle Hackworth   ⁷ , BS ;   Sherif M Badawy   ^{8, 9} , MD ;   Alexis A Thompson   ^{8, 9} , MD ;   Jean L Raphael   ¹⁰ , MD ;   Amber M Yates   ¹¹ , MD ;   Kim Smith-Whitley   ^{12, 13} , MD ;   Allison A King   ^{14, 15} , MD ;   Cecelia Calhoun   ¹⁵ , MD ;   Susan E Creary   ¹⁶ , MD ;   Connie M Piccone   ¹⁷ , MD ;   Aimee K Hildenbrand   ^{18, 19} , PhD ;   Steven K Reader   ^{18, 19} , PhD ;   Lynne Neumayr   ^{20, 21, 22} , MD ;   Emily R Meier   ²³ , MD ;   Amy E Sobota   ²⁴ , MD ;   Sohail Rana   ²⁵ , MD ;   Maria Britto   ^{4, 26, 27} , MD ;   Kay L Saving   ²⁸ , MD ;   Marsha Treadwell   ²⁹ , PhD ;   Charles T Quinn   ^{4, 30} , MD ;   Russell E Ware   ^{4, 5} , MD ;   Lori E Crosby   ^{2, 4, 27} , PsyD

¹ Developmental Neurosciences, Institute of Child Health, University College London, London, United Kingdom

² Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States

³ Department of Psychology, Oklahoma State University, Stillwater, OK, United States

⁴ Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States

⁵ Division of Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States

⁶ Division of General and Community Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, United States

⁷ Cincinnati Children's Hospital Medical Center Partner, Cincinnati, OH, United States

⁸ Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States

⁹ Division of Hematology, Oncology and Stem Cell Transplant, Ann & Robert Lurie Children's Hospital of Chicago, Chicago, IL, United States

¹⁰ Center for Child Health Policy and Advocacy, Baylor College of Medicine, Houston, TX, United States

¹¹ Department of Pediatrics, Division of Hematology/Oncology, Baylor College of Medicine, Houston, TX, United States

¹² Children’s Hospital of Philadelphia, Philadelphia, PA, United States

¹³ Perelman School of Medicine, Philadelphia, PA, United States

¹⁴ Program in Occupational Therapy and Pediatrics, Division of Hematology and Oncology, Washington University School of Medicine and St. Louis Children’s Hospital, St. Louis, MO, United States

¹⁵ Division of Pediatric Hematology/Oncology, Washington University School of Medicine, St. Louis, MO, United States

¹⁶ Center for Innovation in Pediatric Practice, Division of Pediatric Hematology/Oncology/BMT, Nationwide Children's Hospital, Columbus, OH, United States

¹⁷ University Hospitals Rainbow Babies and Children's Hospital, Cleveland, OH, United States

¹⁸ Center for Healthcare Delivery Science, Nemours Children’s Health System, Wilmington, DE, United States

¹⁹ Division of Behavioral Health, Nemours/ Alfred I. duPont Hospital for Children, Wilmington, DE, United States

²⁰ Department of Hematology/Oncology, Children's Hospital Oakland, Oakland, CA, United States

²¹ AbbVie, North Chicago, IL, United States

²² University of California San Francisco, San Francisco, CA, United States

²³ Pediatrics, Pediatric Hematology/Oncology, Indiana Hemophilia and Thrombosis Center, Indianapolis, IN, United States

²⁴ Pediatric Hematology and Oncology, Boston Medical Center, Boston, MA, United States

²⁵ Pediatrics and Child Health, College of Medicine, Howard University, Washington, DC, United States

²⁶ Adolescent and Transition Medicine, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, United States

²⁷ James M. Anderson Center for Health Systems Excellence, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, United States

²⁸ Department of Pediatrics, University of Illinois College of Medicine, Peoria, IL, United States

²⁹ Department of Hematology/Oncology, University of California San Francisco Benioff Children’s Hospital, Oakland, CA, United States

³⁰ Cancer and Blood Diseases Institute, Division of Hematology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, United States